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Invading microorganisms can be sensed through specific pathogen-associated molecular patterns recognized by pathogen recognition receptors on DCs, such as Toll-like receptors (TLRs), C-type lectin receptors, cytosolic Nod-like receptors, and rig-like receptors

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Although there is a strong dose/response relationship between the amount of tobacco smoked per day and cardiovascular risk, the relationship is not linear